MRC Uganda
Job Summary: The position holder will support advanced immunological research and development activities for the VacICoP (Marburg Correlates of Protection) project. The role focuses on the production, optimisation, qualification, and quality assurance of immunological reagents, including recombinant viral antigens and pseudoviruses, to support precision immune assays, vaccine evaluation, and correlates of protection research, in strict compliance with GCLP, biosafety, and quality standards
Key Duties and Responsibilities:
- Produce, optimise, and characterise recombinant viral antigens using mammalian expression systems;
- Generate, titrate, validate, and document pseudoviruses for neutralisation and functional immune assays;
- Support ELISA and neutralisation assay workflows, reagent qualification, and assay optimisation;
- Maintain complete, accurate, and auditable laboratory records in line with GCLP requirements;
- Adhere to biosafety, biosecurity, infection prevention, and cold-chain management procedures;
- Support equipment calibration, environmental monitoring, and quality assurance processes;
- Contribute to monoclonal antibody discovery and antigen‑specific B‑cell workflows;
- Maintain reagent inventories, batch traceability, and SOP compliance; and,
- Support training and supervision of junior staff and trainees
Qualifications, Skills and Experience:
- Bachelor’s degree in medical laboratory technology, Biomedical Sciences, Molecular Biology, Biochemistry, or a related field;
- Should possess 1–2 years’ hands‑on laboratory experience in immunology, molecular biology, cell culture, or protein expression;
- Demonstrated experience with immunoassays and laboratory documentation in regulated environments;
- Training and certification in Biosafety/Biosecurity, IPC, and GCP/GCLP (within the last two years);
- Familiarity with pseudo virus systems, neutralisation assays, and mammalian expression platforms is an added advantage
- Strong attention to detail, data integrity, and ability to execute SOPs reproducibly
- Ability to work independently and collaboratively in a high‑performance R&D environment
Deadline: 21st May 2026
